Types of Research Studies
There are two broad types of research studies: observational studies and clinical trials. Both help improve our understanding and treatment of Alzheimer’s disease and related dementias.
| Observational Studies | Clinical Trials | |
|---|---|---|
| What are they? | Studies that observe what happens naturally, without intervening or giving treatments. | Studies that evaluate new treatments or ways to manage, delay, or prevent disease. |
| Are Medications Administered? | NO | YES |
| How do they work? | Researchers gather information about health, behavior, and other factors over time to observe changes as we age. | People are randomly assigned to receive or not receive a new drug. Information is collected regularly to see how well the drug works. |
| How long do they last? | Typically many years, with participants returning each year. | Can vary from 6 months to over 5 years, with visits throughout the year. |
| How is safety monitored? | Institutional review boards (IRB) ensure studies are ethical and protect the safety and rights of participants. The IRB monitors studies over time to safeguard the welfare of participants. | In addition to the IRB safeguards of observational studies, clinical trials include additional safety monitoring protocols to detect and address any health changes or side effects quickly and effectively. |